Endocrine Abstracts

Polychlorinated biphenyls (PCBs) are persistent environmental pollutants. Two industrial PCB mixtures, Aroclors 1221 and 1254 have been suggested to have estrogenic and anti-estrogenic properties, respectively. We have examined whether these PCB mixtures modulated bone formation and resorption in intact and ovariectomized (ovx) rat models. Twentyfour adult female rats were divided into three groups subcutaneously receiving 4% DMSO (Control), Aroclor 1221 (10 mg/kg) and Aroclor...